Patient has a relevant increase in his asthma symptoms due to environmental allergies. He is currently having salbutamol and fluticasone inhalers. What would you advise as an adjunct medication to treat his symptoms?
The major pathway for the biotransformation of the following compound is by hydrolysis. Identify the site which would be most susceptible to hydrolysis.
The method of ionization of mass spectrometry which results in well-established diagnostic fragmentation patterns that are useful in the identification of compounds of unknown structure is called:
The fraction of bound receptors in a well-defined drug-receptor binding system is determined by:
I the equilibrium drug-receptor dissociation constant
II the free drug concentration
III the total receptor concentration
Side effects that may be expected to occur from the administration of oral contraceptives include all of the following, EXCEPT:
Which of the following agents or combinations may be appropriated to treat severe intermittent asthma?
Goals of gout treatment may include:
I- Reduce inflammation during acute attacks
II- Accelerate renal excretion of uric acid
III- Reduce the conversion of purine to uric acid
When evaluating patients with angina for possible development of nitrate tolerance, true statements include:
I tolerance is rarely associated with isosorbide dinitrate.
II tolerance does not occur in patients who are concurrently on
metoprolol.
III tolerance is dependent upon the administration schedule of nitrate medication.
Drug of choice in the treatment of chronic obstructive pulmonary disease may include:
Which of the following drugs is associated with the reaction of Tendon dyfunction?
For highly polar drugs (e.g. mannitol) what primarily determines elimination rate?
Which of the following is the only polysaccharide NOT synthesized during human metabolism?
All of the following statements concerning the lyophilization of a parenteral product are correct, EXCEPT:
The anatomical divisions of the small intestine include the:
I jejunum
II ileum
III duodenum
In which of the following organs or tissues is the action of acetylcholine NOT described as "nicotinic"?
I Motor endplates of skeletal muscle
II Celiac ganglia
III Circular muscles of the iris
Common etiologic agents of community-acquired pneumonia include:
I Escherichia coli
II Haemophilus influenzae
III Mycoplasma pneumoniae
In the typical cell, mitochondria may contain:
I- Enzymes of Kreb’s cycle
II- Enzymes of respiratory pathway as well cytochrome oxidase
III- Enzymes of fatty acid cycle
Which of the following is considered as essential vitamin for breast-feed babies?
Resistance is the major problem with penicillins due to ability of bacteria to breakdown the lactam ring of penicillin and inactivates the drug. To overcome these problem penicillins can be administrated together with β-lactamase inhibitors.
Examples of β-lactamase inhibitors is/are:
I- Clavulanic acid
II- Sulbactam
III- Tazobactam
Mechanism of inhibit protein synthesis is characteristic of all the following antibiotics, EXCEPT:
Correct statements regarding Pellagra include:
I- Caused due to deficiency of niacin
II- Caused by failure in converting tryptophan to niacin
III- Characterized by dermatitis, diarrhea and dementia